From the American Academy of Ophthalmology

This retrospective review evaluated whether SD-OCT analysis of drusen load at baseline could predict development of advanced AMD in patients with non-neovascular AMD and no retinal pigment epithelial atrophy at baseline. This is the first study to demonstrate that SD-OCT measurements of drusen load, by area (P = .005) or volume (P = .001), can predict RPE atrophy. Additionally, they confirmed the association between drusen load, by area or volume, and development of advanced AMD. Simple and practical, these measurements have potential in routine clinical care and clinical trials. American Journal of Ophthalmology, October 2014